There are different medicines available for blood pressure treatment. In some cases, the medication used to treat blood pressure can cause nightmares in adults. But some individuals are given blood pressure medicine for treating their nightmares. They now may wonder if anyone else has been put on blood pressure medicine for their nightmares. There are conflicting studies regarding this query. One of such medications is prazosin, an alpha-blocker. Prazosin, a blood pressure medication, appears to be an effective treatment for nightmares associated with post-traumatic stress disorder (PTSD).
Study Supporting the Statement
Mayo Clinic psychiatrists present a thorough literature assessment of prazosin in treating nightmares at Prague’s 20th European Congress of Psychiatry. The study looked into 12 prazosin research four randomized controlled trials.
“The tests revealed the medicine was well-tolerated and can take action quickly, within days to weeks, and some patients experienced a return of nightmares when the course of prazosin was discontinued,” says Simon Kung, M.D., the study’s primary investigator and a Mayo Clinic psychiatrist.
“There isn’t much available in terms of drugs for treating nightmares, so prazosin is a promising choice,” Dr. Kung explains.
He went on to say that the literature evaluation opens the door to expanding the use of prazosin. “Because of the modest side effects of prazosin documented in these investigations, it appears logical to extend prazosin use to non-PTSD dreams.”
One of the most disturbing aspects of PTSD is the occurrence of nightmares, specifically, the kinds of dreams that disrupt sleep with terrifying visions of physical or emotional dangers. Nightmares can be so frightening that they contribute to alcoholism, substance misuse, and suicide ideation.
The development of overstimulated chemical messenger norepinephrine receptors in the central nervous system is one proposed cause of nightmare symptoms such as interrupted sleep.
“The notion is that pharmacologic drugs that inhibit these receptors, such as prazosin, may be perfect in treating nightmares,” Dr. Kung explains.
Prazosin is a hypertension medicine that has been utilized by several Veterans Administration facilities to treat PTSD-related nightmares after a decade of research.
Maria Lapid, M.D., of the Mayo Clinic Department of Psychiatry and Psychology, and Zelda Espinel, M.D., M.P.H., of the Universidad El Bosque in Bogota, Colombia, are the other researchers involved in the study.
Now you know that the effect of blood pressure medicines for nightmares has not been proved clearly, and you should consult a specialist to know the facts and get expert advice. If you are using blood pressure medicine for nightmares, consult the specialist to discuss all details. You can book an appointment with the Best Cardiologist in Islamabad to know everything and get expert advice through Marham.
Study Contradicting the Statement
According to a recent study, a medicine used to treat post-traumatic stress disorder (PTSD) may be dangerous. Prazosin, a blood pressure medication, is sometimes used to treat PTSD-related nightmares and insomnia, raising the risk of suicide. However, this short trial reveals that the drug may aggravate nightmares and insomnia while not reducing suicidal ideation in PTSD patients.
Twenty PTSD patients were included in the study, including two military veterans and several civilian women who had been sexually abused. All had active suicidal thoughts, some had tried suicide before, and the majority took antidepressants or had them prescribed for the study.
Participants took prazosin at nighttime for eight weeks to avoid nightmares and suicidal thoughts. Suicidal thoughts, nightmares, insomnia, sadness, and PTSD were assessed every week.
The medicine “didn’t seem to do anything for suicide ideation, which was fairly disappointing,” McCall(chairman of psychiatry and health behavior at the Medical College of Georgia) said in a university news release. “What was mind-blowing was that it worsened nightmares.” “Perhaps it’s not for everyone.”
According to him, the unexpected increase in nightmares and insomnia could be due to the intensity of a patient’s PTSD or the once-daily dose of prazosin. PTSD patients’ nightmares frequently concentrate on the trauma that created their PTSD.
Although two individuals required emergency inpatient psychiatric care, no suicide attempts or deaths occurred during the trial, published in the Journal of Clinical Psychopharmacology.
According to McCall, who is now soliciting advice from PTSD experts across the United States, prazosin may help some PSTD patients. Still, it may not be an intelligent choice when suicide is an active issue.
He also mentioned that two more extensive investigations of inactive and retired military people had mixed results. “We need to reconcile how we have ten years of data claiming prazosin is effective for nightmares in PTSD, a large research last February revealing it has practically no [impact], and now a smaller study showing it can worsen some parts,” McCall said. “We need to understand what it all means.”
He says that the antidepressants sertraline (Zoloft) and paroxetine (Paxil) are the only PTSD medication therapy approved by the U.S. Food and Drug Administration, adding that neither is universally successful.
Frequently Asked Questions (FAQs)
1. What are blood pressure drugs known to produce nightmares?
Beta-blockers lower blood pressure, but they also change how the brain reacts to norepinephrine. Patients taking the beta-blockers have reported nightmares.
2. At what phase of sleep do Trauma nightmares occur?
Doctors refer to nightmare conditions as parasomnia, a sort of sleep disorder characterized by unpleasant experiences that occur while falling asleep, sleeping, or waking up. Nightmares usually appear during the REM (the rapid eye movement) sleep period.
3. What medications can be used for treating nightmares?
Atypical antipsychotics such as olanzapine, risperidone, and aripiprazole may be used to treat PTSD-related nightmares.